Non-Radioactive Detection of Trinucleotide Repeat Size Variability
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چکیده
منابع مشابه
Non-Radioactive Detection of Trinucleotide Repeat Size Variability
Many human diseases are associated with the abnormal expansion of unstable trinucleotide repeat sequences. The mechanisms of trinucleotide repeat size mutation have not been fully dissected, and their understanding must be grounded on the detailed analysis of repeat size distributions in human tissues and animal models. Small-pool PCR (SP-PCR) is a robust, highly sensitive and efficient PCR-bas...
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Many human diseases are associated with the abnormal expansion of unstable trinucleotide repeat sequences. The mechanisms of trinucleotide repeat size mutation have not been fully dissected, and their understanding must be grounded on the detailed analysis of repeat size distributions in human tissues and animal models. Small-pool PCR (SP-PCR) is a robust, highly sensitive and efficient PCR-bas...
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ژورنال
عنوان ژورنال: PLoS Currents
سال: 2014
ISSN: 2157-3999
DOI: 10.1371/currents.md.ad50113b899fa1352ce70c087eead706